The success of Barbie was a major portion of the monologue, particularly Greta Gerwig's lack of a Best Director nomination. When he noted that most people thought she should deserved to get a nod, she got a round of applause, at which point Kimmel shot back, "I know you're clapping but you're the ones who didn't vote for her by the way. Don't act like you had nothing to do with this."
When talking about Emma Stone's Poor Things character he cracked, "Emma played an adult woman with the brain of a child, like the lady who gave the rebuttal to the State of the Union on Thursday night," referring to Alabama senator Katie Britt.
He also called out the length of many of this year's nominated films, mentioning that the average length of the top 10 movies was two hours and 23 minutes. Speaking of Martin Scorsese's Killers of the Flower Moon in particular he noted, "in the time it takes you to watch it you could drive to Oklahoma and solve the murders yourself."